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Antigenic Specificity | SOCS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat. predicted: mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for Suppressor of cytokine signaling 1(SOCS1) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: Suppressor of cytokine signaling 1(SOCS1), also known as Jak-binding protein(JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity. The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13. SOCS1 regulates the JAK/STAT signal-transduction pathway. Moreover, it contributes to protection against hepatic injury and fibrosis, |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human SOCS1, identical to the related mouse and rat sequences. |
Other Names | [Suppressor of cytokine signaling 1(SOCS-1); suppressor of cytokine signaling 1; CISH 1; CISH1; Cytokine Inducible SH2 Protein 1; JAB; JAK Binding Protein; JAK-binding protein; Janus kinase binding protein; SOCS 1; SOCS-1; Socs1; SOCS1_HUMAN; SSI 1; SSI-1; SSI1; STAT Induced STAT Inhibitor 1; STAT-induced STAT inhibitor 1; Suppressor of cytokine signaling 1; Supressor of cytokine Signalling 1; TEC Interacting Protein 3; Tec-interacting protein 3; TIP 3; TIP-3; TIP3], [SOCS1; SOCS1; JAB; CIS1; SSI1; TIP3; CISH1; SSI-1; SOCS-1; SSI1; TIP3; SOCS-1; JAB; SSI-1; TIP-3] |
Gene, Accession # | [SOCS1], Gene ID: 8651, NCBI: O15524.1, UniProt: O15524 |
Catalog # | MBS175557 |
Price | $315 |
Order / More Info | SOCS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |