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Antigenic Specificity | MAK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MAK antibody detects endogenous levels of total MAK. Function: Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors (By similarity). Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells.Subunit Structure: Interacts with RP1 (By similarity). Interacts with AR and CDK20. Found in a complex containing MAK, AR and NCOA3. Interacts with FZR1 (via WD repeats).Post-translational Modifications: Autophosphorylated. Phosphorylated on serine and threonine residues.Similarity: Belongs to the protein kina |
Immunogen | Immunogen: A synthesized peptide derived from human MAK Subcellular Location: Nucleus. Cytoplasm > Cytoskeleton > Centrosome. Cytoplasm > Cytoskeleton > Spindle. Midbody. Cell projection > Cilium > Photoreceptor Outer Segment. Photoreceptor Inner Segment. Localized in both the connecting cilia and the outer segment axonemes (By similarity). Localized uniformly in nuclei during interphase, to the mitotic spindle and centrosomes during metaphase and anaphase, and also to midbody at anaphase until |
Other Names | [intestinal cell kinase; dJ417M14.2; fj04c02; Ick; Mak; MAK_HUMAN; Male germ cell associated kinase; Male germ cell-associated kinase; male germ cell-associated kinase retinal-enriched isoform; OTTHUMP00000016025; Rck; RP62; Serine/threonine protein kinase MAK; Serine/threonine-protein kinase MAK; testicular secretory protein Li 28; wu:fj04c02; zgc:56603] |
Gene, Accession # | [MAK], Gene ID: 4117, NCBI: NP_001229314.1, UniProt: P20794 |
Catalog # | MBS9608992 |
Price | $240, $280 |
Order / More Info | MAK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |