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Antigenic Specificity | MEK5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total MEK5 protein. A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phospho-rylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resem-bles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphory-late ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa. 311-315(K-T-Y-V-G) derived from Rat MEK5. |
Other Names | [MAP kinase kinase 5; Map2k5; MAPKK 5; MAPK/ERK kinase 5] |
Gene, Accession # | [MEK5], Gene ID: 29568, NCBI: NP_001029159.1, UniProt: Q62862 |
Catalog # | MBS9410706 |
Price | $200, $255 |
Order / More Info | MEK5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |