Calretinin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Calretinin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, monkey, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 5 mL |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Formalin/Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody is suitable for the detection of Calretinin in neurons and may be used as an aid in differential diagnosis of pleura-mesothelioma. This marker is frequently expressed in epitheloid mesothelioma, while occasionally it turns positive in sarcomatous mesothelioma and carcinoma. It was found to be negative in sarcoma (2,3) and in 90% of adenocarcinoma. Calretinin is a Calcium-binding protein related to Calmodulin and Calbindin. It is found in groups of neurons of the brain cortex, in the retina and in the spinal cord (1). More recent studies show that it is a suitable marker for mesothelioma of the lung (2, 3, 4, 5). Calretinin. |
| Immunogen | Immunogen: Recombinant human Calretinin |
| Other Names | [calretinin isoform 1; Calretinin; calretinin; calbindin 2; 29 kDa calbindin], [CALB2; CALB2; CR; CAL2; CAB29; CAB29; CR] |
| Gene, Accession # | Gene ID: 794, NCBI: NP_001731.2, UniProt: P22676 |
| Catalog # | MBS397039 |
| Price | $280 |
| Order / More Info | Calretinin Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Schwaller B., Buchwald P., Blumcke I., Celio M.R., and Hunziker W. (1994) Characterization of a polyclonal antiserum against the purified human recombinant calcium binding protein calretinin. Cell Calcium 14; 639-648. 2. Gotzos V., Vogt P., and Celio M.R. (1995) Calretinin is a selective marker for malignant pleural mesotheliomas of the epithelial type. Pathol. Res. Pract. 192; 137-147. 3. Doglioni C., Tos A.P., Laurino L., Iuzzolino P., Chiarelli C., Celio M.R., and Viale G. (1996) Calretinin: a novel immunohistochemical marker for mesothelioma. Am. J. Surg. Pathol. 20; 1037-1046. 4. Wiethege T., Philips S. und Muller K.-M. (1997) Calretinin in Mesotheliomen und pulmonalen Adenokarzinomen. Ein differentialdiagnostischer Marker. Atemw. Lungenkrkh. 23(7); 410-411. 5. Muller K.-M. (1997) Mesotheliome, Pathologie/Pathogenese/Mesotheliomregister Pneumologie 51; 335-344. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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