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Antigenic Specificity | HSPB8 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, goat, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against HSPB8. It was validated on Western Blot using a cell lysate as a positive control.Target Description: HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 protein is induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in the encoding HSPB8 gene have been associated with different neuromuscular diseases, including Charcot-Marie-Toot |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HSPB8 |
Other Names | [heat shock protein beta-8; Heat shock protein beta-8; heat shock protein beta-8; heat shock protein family B (small) member 8; Alpha-crystallin C chain; E2-induced gene 1 protein; Protein kinase H11; Small stress protein-like protein HSP22] |
Gene, Accession # | [HSPB8], Gene ID: 26353, NCBI: NP_055180, UniProt: Q9UJY1 |
Catalog # | MBS3212014 |
Price | $335 |
Order / More Info | HSPB8 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |