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Antigenic Specificity | IL-23R |
Clone | [ABM25G4] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-23, a member of the IL-12 cytokine family, is composed of a p40 subunit, which is shared with IL-12, and a p19 subunit, with an approximate molecular weight of 60 kDa. IL-23 is produced by activated dendritic cells and macrophages in response to microorganisms. IL-23 promotes Th17 cells producing TNF-a, IL-17, IL-6, IL-22, GM-CSF, and other novel factors, which are associated with the induction of autoimmune inflammation. IL-23 is essential for Th17 differentiation, expansion, and survival by binding to its receptor, thereby activating the signaling pathway. Many studies revealed that the IL-23/Th17 pathway is implicated in the pathophysiology of various autoimmune diseases, such as autoimmune arthritis, primary biliary cirrhosis, and in |
Immunogen | Antigen: IL-23R. Immunogen Information: A partial length recombinant protein (a.a 250-450) of IL-23R was used as the immunogen for this antibody. Conjugation: Unconjugated |
Other Names | [Interleukin-23 receptor; IL-23 receptor; IL-23R], [IL23R] |
Gene, Accession # | [IL-23R], Gene ID: 149233, NCBI: NP_653302.2, UniProt: Q5VWK5 |
Catalog # | MBS668975 |
Price | $290 |
Order / More Info | IL-23R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |