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Antigenic Specificity | VGLUT2 |
Clone | [S29-29] |
Host Species | Mouse |
Reactive Species | mouse, rat |
Isotype | IgG1 |
Format | ATTO 488 conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects ~60kDa. Scientific Background: The ATP-dependent, chloride-sensitive vesicular glutamate transporters (VGLUT) include BNPI (VGLUT1), VGLUT2 (DNPI) and VGLUT3. The brain expresses BNPI (brain specific Na -dependent inorganic phosphate (Pi) cotransporter) and VGLUT2 in a complementary fashion. The telencephalic regions express BNPI, whereas the lower brainstem and diencephalic regions express VLGUT2. Rat pinealocytes express both BNPI and VGLUT2. The striatum, hippocampus, cerebral cortex and raphe nuclei express VGLUT3 in a small number of neurons. Pancreatic alpha and beta cells express BNPI and VGLUT2 in response to glucose concentrations. Human VGLUT3 shares a 72% sequence homology with VLGUT2 and BNPI. |
Immunogen | n/a |
Other Names | [Differentiation associated BNPI; DNPI; SLC17A6; Solute carrier family 17 member 6; Vesicular glutamate transporter 2; Differentiation associated Na dependent inorganic phosphate cotransporter], [Slc17a6; Slc17a6; Dnpi; Vglut2; Dnpi; Vglut2; VGluT2] |
Gene, Accession # | Gene ID: 84487, NCBI: NP_445879.1, UniProt: Q9JI12 |
Catalog # | MBS800454 |
Price | $440 |
Order / More Info | VGLUT2 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Aihara Y., et al. (2000) J Neurochem. 74: 2622-2625. 2. Kaneko T., and Fujiyama F. (2002) Neurosci Res. 42: 243-250. 3. Gras C., et al. (2002) J Neurosci. 22: 5442-5451. 4. Takamori S., Malherbe P., Broger C., and Jahn R. (2002) EMBO Rep. 3: 798-803. 5. Morimoto R., Hayashi M., Yatsushiro S., Otsuka M., Yamamoto A., and Moriyama Y. (2003) J Neurochem. 84: 382-391. 6. Bai L., Zhang X., and Ghishan F.K. (2003) Am. J. Physiol. Gastrointest. Liver Physiol. 284: G808-814. |