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Antigenic Specificity | Human MYD88 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: peptide corresponding to amino acids 233 to 248 of human MyD88, which differ from those of mouse by two amino acids. The pro-inflammatory cytokine IL-1 induced cellular response requires IL-1 receptor complex including IL-1RI and IL-1RAcP. Recently, MyD88 was identified as an adapter molecule in the IL-1 signaling pathway. MyD88 associates with and recruits IRAK to the IL-1 receptor complex in response to IL-1 treatment and dominant negative form of MyD88 attenuates IL-1R-mediated NF-kB activation. |
Immunogen | Immunogen Description: Synthetic peptide from human MYD88. |
Other Names | [MYD88 (aa233-248) IHC-plus; MYD88; MYD88D; Human MYD88], [MYD88; MYD88; MYD88D] |
Gene, Accession # | [MYD88], Gene ID: 4615, NCBI: NP_002459.2, UniProt: Q99836 |
Catalog # | MBS241295 |
Price | $530 |
Order / More Info | Human MYD88 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |