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Antigenic Specificity | TESC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, rabbit, dog |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TESC Antibody detects endogenous levels of TESC. Description: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.Subunit Structure: Monomer. Homodimer; disulfide-linked (By similarity). Interacts |
Immunogen | Immunogen: A synthesized peptide derived from human TESC. Tissue Specificity: Expressed in mature megakaryocytes and polymorphonuclear granulocytes (at protein level). Abundantly expressed in heart. Also expressed at a lower level in adult testis and salivary gland, and in the placenta. |
Other Names | [1010001A17Rik; Calcineurin B homologous protein 3; CHP3; FLJ20607; MGC117906; OTTHUMP00000185561; OTTMUSP00000023573; TE 1; Tescalcin; TSC] |
Gene, Accession # | [TESC], Gene ID: 54997, NCBI: NP_001161797.1, UniProt: Q96BS2 |
Catalog # | MBS9611520 |
Price | $240, $280 |
Order / More Info | TESC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |