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Antigenic Specificity | Human Neuropilin-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood ve |
Immunogen | Immunogen: Recombinant human Neuropilin-1 protein(684-923aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7239 / sc-5541 |
Other Names | [Vascular endothelial cell growth factor 165 receptor; NRP1; NRP; VEGF165R], [NRP1; NRP1; NP1; NRP; BDCA4; CD304; VEGF165R; NRP; VEGF165R] |
Gene, Accession # | [NRP1], Gene ID: 8829, NCBI: NP_001019799.1, UniProt: O14786 |
Catalog # | MBS1498712 |
Price | $120, $160 |
Order / More Info | Human Neuropilin-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |