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Antigenic Specificity | Human Proto-oncogene Mas |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1. |
Immunogen | Immunogen: Recombinant human Proto-oncogene Mas protein (246-325aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54682 / sc-54846 |
Other Names | [MAS1; MAS], [MAS1; MAS1; MAS; MGRA; MAS] |
Gene, Accession # | [MAS1], Gene ID: 4142, NCBI: NP_002368.1, UniProt: P04201 |
Catalog # | MBS1495597 |
Price | $120, $160 |
Order / More Info | Human Proto-oncogene Mas Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |