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Antigenic Specificity | DICER1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin fo |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1460 of human DICER1 (NP 085124.2). |
Other Names | [DCR1; MNG1; Dicer; HERNA; RMSE2; Dicer1e; K12H4.8-LIKE] |
Gene, Accession # | [DICER1], Gene ID: 23405, NCBI: NP_001182502.1, UniProt: Q9UPY3 |
Catalog # | MBS8545894 |
Price | $280 |
Order / More Info | DICER1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |