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Antigenic Specificity | Human CD70 |
Clone | [Bu69] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.2 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Frozen, Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD70 antibody, clone Bu69 recognises human CD70, also known as CD27 ligand (CD27-L) or Tumor necrosis factor ligand superfamily member 7. CD70 is a 193 amino acid ~29kDa single pass type II transmembrane glycoprotein belonging to the tumour necrosis factor (TNF) family (UniProt: P32970). CD70 is expressed on a small number of activated T-cells and the majority of activated B-cells (Bowman et al. 1994). Interaction of CD70 with its receptor, CD27, is thought to play an important role in lymphocyte activation, proliferation, survival and differentiation (Hintzen et al. 1994). Mouse anti Human CD70 antibody, clone Bu69 has been used for the inhibition of neural stem cell induced apoptosis of allogeneic T cells in vitro (Lee et |
Immunogen | n/a |
Other Names | [CD70 antigen; CD70 antigen; CD70 antigen; CD27 ligand; CD27-L; Ki-24 antigen; surface antigen CD70; tumor necrosis factor (ligand) superfamily, member 7; tumor necrosis factor ligand superfamily member 7; CD70 molecule; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD_antigen: CD70], [CD70; CD70; CD27L; CD27LG; TNFSF7; CD27L; CD27LG; TNFSF7; CD27-L] |
Gene, Accession # | [CD70], Gene ID: 970, NCBI: NP_001243.1, UniProt: P32970 |
Catalog # | MBS214279 |
Price | $430 |
Order / More Info | Human CD70 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |