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Antigenic Specificity | HOXA9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HOXA9 is a well-studied member of the HOXA cluster, and it plays a significant role in both normal hematopoiesis and leukemogenesis. HOXA9 is expressed in EC (Endothelial Cells) and its expression is rapidly downregulated during EC activation by inflammatory signals like TNF-alpha (Tumor Necrosis Factor-Alpha) and LPS (lipopolysaccharide). In humans, HOXA9 was found to be highly expressed and required in some subtypes of leukemia, particularly mixed lineage leukemia (MLL)-rearranged leukemia. The aberrant overexpression of HOXA9 is thought to be associated with poor survival of acute myeloid leukemia (AML) patients. |
Immunogen | Immunogen Information: A partial length recombinant HOXA9 protein (amino acids 63-272) was used as the immunogen for this antibody. |
Other Names | [HOXA9; HOX1G; Homeobox protein Hox-1G; to HOXA9; HOXA9; HOXA9], [HOXA9; HOXA9; HOX1; ABD-B; HOX1G; HOX1.7; HOX1G] |
Gene, Accession # | [HOXA9], Gene ID: 3205, NCBI: P31269.4, UniProt: P31269 |
Catalog # | MBS668680 |
Price | $270 |
Order / More Info | HOXA9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |