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Antigenic Specificity | ZIP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The zinc transporter ZIP2, also known as SLC39A2, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP3, ZIP2-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adeno |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 17 amino acid peptide near the amino terminus of human ZIP2. |
Other Names | [Solute carrier family 39 member A2, Slc39A2, 6A1, Eti-1] |
Gene, Accession # | [ZIP2], Gene ID: 29986, NCBI: NP_055394 |
Catalog # | MBS9411798 |
Price | $320 |
Order / More Info | ZIP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |