Phospho Ser1244 NMDA Receptor, NR2C Subunit Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho Ser1244 NMDA Receptor, NR2C Subunit |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Specific for the ~140k NR2C subunit of the NMDA receptor phosphorylated at Ser1244. Immunolabeling is blocked by preadsorption of antibody with the phospho-peptide that was used to generate the antibody but not by the corresponding dephospho-peptide. Affinity purified rabbit polyclonal antibody |
| Immunogen | Antigen: Synthetic phospho-peptide surrounding the phospho Ser1244 of the NR2C-subunit of rat NMDA receptor. Immunogen Information: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1244 conjugated to KLH. Immunogen Species: Rat |
| Other Names | [glutamate receptor ionotropic, NMDA 2C; Glutamate receptor ionotropic, NMDA 2C; glutamate receptor ionotropic, NMDA 2C; NMDAR2C; NMDA glutamate receptor; glutamate receptor, ionotropic, NMDA2C; N-methyl D-aspartate receptor subtype 2C; glutamate [NMDA] receptor subunit epsilon-3; glutamate receptor, ionotropic, N-methyl D-aspartate 2C; Glutamate [NMDA] receptor subunit epsilon-3; N-methyl D-aspartate receptor subtype 2C], [Grin2c; Grin2c; NR2C; GluN2C; GluN2C; NMDAR2C; NR2C] |
| Gene, Accession # | [GRIN2C], Gene ID: 24411, NCBI: NP_036707.3, UniProt: Q00961 |
| Catalog # | MBS502150 |
| Price | $360 |
| Order / More Info | Phospho Ser1244 NMDA Receptor, NR2C Subunit Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Alvestad RM, Grosshans DR, Coultrap SJ, Nakazawa T, Yamamoto T, Browning MD (2003) Tyrosine dephosphorylation and ethanol inhibition of N-methyl-D-aspartate receptor function. J Biol Chem 278:11020-11025.• Carroll RC, Zukin RS (2002) NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity. Trends Neurosci 25:571-577.• Ebralidze AK, Rossi DJ, Tonegawa S, Slater NT (1996) Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene. J Neurosci 16:5014-5025.• Grosshans DR, Clayton DA, Coultrap SJ, Browning MD (2002) LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1. Nat Neurosci 5:27-33.• Lovinger DM, White G, Weight FF (1989) Ethanol inhibits NMDA-activated ion current in hippocampal neurons. Science 243:1721-1724. |
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