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Antigenic Specificity | DOK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DOK1 Antibody: Signals from most growth factors and cytokines are transduced by receptor tyrosine kinases or non-receptor tyrosine kinases. Activated tyrosine kinases phosphorylate their substrates, which mediate the cellular response to extracellular stimuli. A long-sought major substrate termed p62dok (downstream of tyrosine kinase) for many tyrosine kinases including c-kit, v-abl, v-Fps, v-Src, v-Fms, and activated EGF, PDGF, IGF, VEGF and insulin receptors was identified recently from human and mouse by several laboratories. Upon phosphorylation, p62dok forms a complex with the ras GTPase-activating protein (RasGAP). p62dok represents a new family with very recently identified p56dok. |
Immunogen | Immunogen: DOK1 antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human DOK1. Buffer: DOK1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [DOK1; TP1; TLP1; p240; TROVE1; VAULT2; Docking protein 1; Downstream of tyrosine kinase 1; telomerase-associated protein 1], [TEP1; TEP1; TP1; TLP1; p240; TROVE1; VAULT2; TLP1; TP1; Telomerase protein 1] |
Gene, Accession # | [TEP1], Gene ID: 7011, NCBI: AAC51127, UniProt: Q99704 |
Catalog # | MBS151146 |
Price | $375 |
Order / More Info | DOK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |