UNG Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | UNG |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | When misincorporation or cytosine deamination positions the RNA nucleotide uracil into DNA, uracilDNA gycosylase (UDG) excises the uracil via a repair enzymatic pathway. This is done by cleaving the NC1' gylcosylic bond between the base and deoxyribose, in both single and doublestranded DNA. While initiating the first steps of DNA repair, UDG undergoes a conformational change from the open unbound state to the closed DNAbound state, creating a catalytic center. The bound UDG effectively flips the uridine nucleotide into the catalyic center and cleaves the glycosylic bond to excise the uracil. The opentoclosed conformation change is centered on a B zipper in the UDG. UDG alters the orientation electron orbitals to favor electron transpos |
| Immunogen | Immunogen: A synthetic peptide of human UNG |
| Other Names | [UNG; UNG; DGU; DKFZp781L1143; HIGM4; UDG; UNG1; UNG15; UNG2; UracilDNA glycosylase], [UNG; UNG; DGU; UDG; UNG1; UNG2; HIGM4; HIGM5; UNG15; DGU; UNG1; UNG15; UDG] |
| Gene, Accession # | Gene ID: 7374, NCBI: NP_003353.1, UniProt: P13051 |
| Catalog # | MBS128010 |
| Price | $200, $275, $430 |
| Order / More Info | UNG Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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