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Antigenic Specificity | BAT1 (C-term), 351-380 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, rat, bovine, chicken, Drosophila, porcine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This BAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-380 amino acids from the C-terminal region of human BAT1. Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. UAP56 functions as a bridge between THOC4 and the THO complex. The TREX complex is es |
Immunogen | n/a |
Other Names | [Spliceosome RNA helicase DDX39B; 56 kDa U2AF65-associated protein; ATP-dependent RNA helicase p47; DEAD box protein UAP56; HLA-B-associated transcript 1 protein; DDX39B; BAT1; UAP56] |
Gene, Accession # | [DDX39B], Gene ID: 7919, NCBI: NP_004631.1, UniProt: Q13838 |
Catalog # | MBS9211814 |
Price | $165, $370 |
Order / More Info | BAT1 (C-term), 351-380 Antibody from MYBIOSOURCE INC. |
Product Specific References | Choudhary C., et.al., Science 325:834-840(2009). Boyne J.R., et.al., PLoS Pathog. 4:E1000194-E1000194(2008). |