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Antigenic Specificity | CD271 (Tumor necrosis factor receptor superfamily member16) |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of CD271. NGFR p75 or CD271 is a 75kD transmembrane glycoprotein consisting of an extracellular domain which contains four cysteine rich domains responsible for ligand binding, a transmembrane domain, and a cytoplasmic domain. NGFR p75 displays paradoxical functions when acting alone or with other receptor proteins. Working in concert with Trk receptors, it recognizes neurotrophins and transmits trophic signals into the cell. NGFR p75 is necessary for regulating neuronal growth, migration, differentiation and cell death during development of the central and peripheral nervous system. |
Immunogen | n/a |
Other Names | [Tumor necrosis factor receptor superfamily member 16; Tumor necrosis factor receptor superfamily member 16; tumor necrosis factor receptor superfamily member 16; nerve growth factor receptor (TNFR superfamily, member 16); Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; CD_antigen: CD271], [Ngfr; Ngfr; p75; LNGFR; p75NTR; p75NGFR; Tnfrsf16; Tnfrsf16; NGF receptor] |
Gene, Accession # | [CD271], Gene ID: 18053, NCBI: Q9Z0W1.1, UniProt: Q9Z0W1 |
Catalog # | MBS857122 |
Price | $280 |
Order / More Info | CD271 (Tumor necrosis factor receptor superfamily member16) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Low-affinity nerve-growth factor receptor (p75NTR) can serve as a receptor for rabies virus.Tuffereau C., Benejean J., Blondel D., Kieffer B., Flamand A.EMBO J. 17:7250-7259(1998). 2. Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry.Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J., Faessler R., Mann M.J. Proteome Res. 7:5314-5326(2008). |