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Antigenic Specificity | EIF2S2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-175 of human EIF2S2 (NP 003899.2). |
Other Names | [EIF2; EIF2B; PPP1R67; EIF2beta; eIF-2-beta] |
Gene, Accession # | [EIF2S2], Gene ID: 8894, NCBI: NP_003899.2, UniProt: P20042 |
Catalog # | MBS8549475 |
Price | $280 |
Order / More Info | EIF2S2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |