SKI Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SKI |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mousepredicted: bovine, horse, dog, chicken, Xenopus |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Peptide ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: SKI Antibody detects endogenous levels of SKI. Description: May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling.Post Translational Modifications: Ubiquitinated by RNF165, promoting proteasomal degradation, leading to enhance the BMP-Smad signaling.Subunit Structure: Interacts with SMAD2, SMAD3 and SMAD4. Interacts with HIPK2. Part of a complex with HIPK2 and SMAD1/2/3. Interacts with PRDM16 and SMAD3; the interaction with PRDM16 promotes the recruitment SMAD3-HDAC1 complex on the promoter of TGF-beta target genes.Similarity: Belongs to the SKI family. |
| Immunogen | Immunogen: A synthesized peptide derived from human SKI. |
| Other Names | [Avian sarcoma viral (v ski) oncogene homolog; C oncogene; C ski; Proto-oncogene c-Ski; SKI; Ski oncogene; Ski oncoprotein; SKI_HUMAN; SKV; v ski avian sarcoma viral oncogene homolog; v ski sarcoma viral oncogene homolog] |
| Gene, Accession # | [SKI], Gene ID: 6497, NCBI: P12755.1, UniProt: P12755 |
| Catalog # | MBS9610824 |
| Price | $225, $280, $340 |
| Order / More Info | SKI Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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