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Antigenic Specificity | TREML1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Trem-like transcript 1 protein(TREML1) detection. Background: Trem-like transcript 1 protein is a protein that in humans is encoded by the TREML1 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. |
Immunogen | Immunogen: E. coli-derived human TREML1 recombinant protein (Position: Q16-P162). Human TREML1 shares 69.3% amino acid (aa) sequence identity with mouse TREML1. |
Other Names | [GLTL1825; PRO3438; TLT 1; TLT-1; TLT1; TREML 1; Treml1; Q86YW5; Trem-like transcript 1 protein; triggering receptor expressed on myeloid cells like 1], [TREML1; TREML1; TLT1; TLT-1; PRO3438; GLTL1825; dJ238O23.3; TLT1; TLT-1] |
Gene, Accession # | [TREML1], Gene ID: 340205, NCBI: NP_001258736.1, UniProt: Q86YW5 |
Catalog # | MBS178705 |
Price | $280 |
Order / More Info | TREML1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: TREML1 triggering receptor expressed on myeloid cells-like 1.2. Allcock RJ, Barrow AD, Forbes S, Beck S, Trowsdale J (Mar 2003). The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44. Eur J Immunol. 33(2): 567-77.3. Washington AV, Quigley L, McVicar DW (Nov 2002). Initial characterization of TREM-like transcript (TLT)-1: a putative inhibitory receptor within the TREM cluster. Blood. 100 (10): 3822-4. |