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Antigenic Specificity | IL27 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Associates with EBI3 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WS |
Immunogen | Immunogen: Recombinant human Interleukin-27 subunit alpha protein(29-243aa) |
Other Names | [IL-27 subunit alpha; IL-27-A; IL27-A; Interleukin-30; IL27; IL27A; IL30], [IL27; IL27; p28; IL30; IL-27; IL27A; IL-27A; IL27p28; IL27A; IL30; IL-27 subunit alpha; IL-27-A; IL27-A] |
Gene, Accession # | [IL27], Gene ID: 246778, NCBI: NP_663634.2, UniProt: Q8NEV9 |
Catalog # | MBS1494910 |
Price | $120, $160 |
Order / More Info | IL27 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |