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Antigenic Specificity | DOK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Signals from most growth factors and cytokines are transduced by receptor tyrosine kinases or non-receptor tyrosine kinases. Activated tyrosine kinases phosphorylate their substrates, which mediate the cellular response to extracellular stimuli. A long-sought major substrate termed p62dok (downstream of tyrosine kinase) for many tyrosine kinases including c-kit, v-abl, v-Fps, v-Src, v-Fms, and activated EGF, PDGF, IGF, VEGF and insulin receptors was identified recently from human and mouse by several laboratories. Upon phosphorylation, p62dok forms a complex with the ras GTPase-activating protein (RasGAP). p62dok represents a new family with very recently identified p56dok. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a peptide corresponding to amino acids near the carboxy terminus of human DOK1. |
Other Names | [GAP binding protein p62dok; Docking protein 1; docking protein 1; docking protein 1, 62kDa (downstream of tyrosine kinase 1); Downstream of tyrosine kinase 1; p62(dok); pp62] |
Gene, Accession # | [DOK1], Gene ID: 1796, NCBI: AAC51127 |
Catalog # | MBS9413453 |
Price | $320 |
Order / More Info | DOK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |