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Antigenic Specificity | LAMP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plays an important role in chaperone-mediated autophagy, a process that mediates lysosomal degradation of proteins in response to various stresses and as part of the normal turnover of proteins with a long biological half-live (PubMed:8662539, PubMed:11082038, PubMed:18644871, PubMed:24880125, PubMed:27628032). Functions by binding target proteins, such as GAPDH and MLLT11, and targeting them for lysosomal degradation (PubMed:8662539, PubMed:11082038, PubMed:18644871, PubMed:24880125). Plays a role in lysosomal protein degradation in response to starvation. Required for the fusion of autophagosomes with lysosomes during autophagy (PubMed:27628032). Cells that lack LAMP2 express normal levels of VAMP8, but fail to accumulate STX17 on autopha |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-300 of human LAMP2 (NP 054701.1). |
Other Names | [LAMPB; CD107b; LAMP-2; LGP-96; LGP110] |
Gene, Accession # | [LAMP2], Gene ID: 3920, NCBI: P13473.2, UniProt: P13473 |
Catalog # | MBS8549301 |
Price | $280 |
Order / More Info | LAMP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |