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Antigenic Specificity | PRICKLE2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Two isoforms of PRICKLE2 are known to exist. PRICKLE2 antibody is predicted to not cross-react with other PRICKLE protein family members. PRICKLE2, also known as Pk2 or EPM5, is a member of a highly conserved protein family that function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity. Both PRICKLE2 and the related protein PRICKLE1 are expressed in postmitotic neurons and promote neurite outgrowth, and both proteins promote neurite outgrowth via the Dishevelled dependent pathway in C1300 cells. PRICKLE2 localizes to the postsynaptic density and interacts with PSD-95 and NMDA receptors. Defects in the gene encoding PRICKLE2 are associated with autosomal recessive p |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 15 amino acid peptide near the center of human PRICKLE2. |
Other Names | [REST, NRSF-interacting LIM domain protein 1, Pk2, EPM5] |
Gene, Accession # | [PRICKLE2], Gene ID: 166336, NCBI: NP_942559 |
Catalog # | MBS9401999 |
Price | $320 |
Order / More Info | PRICKLE2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |