Edit |   |
Antigenic Specificity | CTCF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CTCF antibody detects endogenous levels of total CTCF. Description: CCCTC-binding factor (CTCF) and its paralog, the Brother of the Regulator of Imprinted Sites (BORIS), are highly conserved transcription factors that regulate transcriptional activation and repression, insulator function, and imprinting control regions (ICRs) (1-4). Although they have divergent amino and carboxy termini, both proteins contain 11 conserved zinc finger domains that work in combination to bind the same DNA elements (1). CTCF is ubiquitously expressed and contributes to transcriptional regulation of cell-growth regulated genes, including c-myc, p19/ARF, p16/INK4A, BRCA1, p53, p27, E2F1, and TERT (1). CTCF also binds to and is required for the enhan |
Immunogen | Immunogen: A synthesized peptide derived from human CTCF Subcellular Location: Nucleus > Nucleoplasm. Chromosome. Chromosome > Centromere. May translocate to the nucleolus upon cell differentiation. Associates with both centromeres and chromosomal arms during metaphase. Associates with the H19 ICR in mitotic chromosomes. May be preferentially excluded from heterochromatin during interphase. Tissue Specificity: Ubiquitous. Absent in primary spermatocytes. Predicted Cross React |
Other Names | [11 zinc finger protein; 11 zinc finger transcriptional repressor; 11-zinc finger protein; CCCTC binding factor (zinc finger protein); CCCTC binding factor; CCCTC-binding factor; Ctcf; CTCF_HUMAN; CTCFL paralog; MRD21; Transcriptional repressor CTCF] |
Gene, Accession # | [CTCF], Gene ID: 10664, NCBI: NP_001177951.1, UniProt: P49711 |
Catalog # | MBS9606926 |
Price | $240, $280 |
Order / More Info | CTCF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |