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Antigenic Specificity | Human CD127 |
Clone | [ANC8F2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1k |
Format | unconjugated |
Size | 120 tests |
Concentration | Volume: 0.2ml |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Information: CD127 (IL-7Ra) is the specific receptor component for the cytokine Interleukin -7 (IL-7). It is found on a wide variety of hematopoietic cell types including B cell precursors, and the majority of T cells. Its expression levels are decreased on T cells following activation. CD127 can dimerize with CD132(IL-2Rg) to form a high affinity IL-7 receptor (1). CD127 engagement is necessary for T cell development in humans (2). Antibody ANC8F2 recognizes an extracellular epitope of recombinant and native CD127 in FACS and Enzyme Immunoassay. |
Immunogen | Immunogen: Recombinant human CD127 |
Other Names | [human CD127 (IL-7Ra)/FITC], [IL7R; CD127; CD127] |
Gene, Accession # | [CD127], Gene ID: 100271930, NCBI: CAM57334.1, UniProt: B9ZSM5 |
Catalog # | MBS666250 |
Price | $440 |
Order / More Info | Human CD127 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1) Noguchi, M. et al., 1993, Science 262:1877. 2) Pribyl, J.A. and T.W. LeBien, 1996, Proc. Natl. Acad. Sci. 93:10348. 3) Goodwin RG, Friend D, Ziegler SF, et al. Cell. 1990;60:941. |