TXNIP Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TXNIP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TXNIP antibody detects endogenous levels of total TXNIP. Function: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mam |
| Immunogen | Immunogen: A synthesized peptide derived from human TXNIP Subcellular Location: Cytoplasm. Tissue Specificity: By 1, 25-dihydroxyvitamin D-3 and TGFB1. Down-regulated in response to oxidative stress. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog, Xenopus Similarity: Pig (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%), Xenopus (82%) |
| Other Names | [EST01027; HHCPA78; THIF; Thioredoxin binding protein 2; Thioredoxin interacting protein; Thioredoxin-binding protein 2; Thioredoxin-interacting protein; TXNIP; TXNIP_HUMAN; Upregulated by 1, 25 dihydroxyvitamin D 3; VDUP1; Vitamin D3 up-regulated protein 1] |
| Gene, Accession # | [TXNIP], Gene ID: 10628, NCBI: NP_001300901.1, UniProt: Q9H3M7 |
| Catalog # | MBS9608116 |
| Price | $240, $280 |
| Order / More Info | TXNIP Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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