Edit |   |
Antigenic Specificity | MR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Frozen, Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), Direct ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for MR1 detection. Tested with WB, IHC-F, ICC, FCM, Direct ELISA in Human; Mouse; Rat.Background: Major histocompatibility complex class I-related gene protein is a protein that in humans is encoded by the MR1 gene. MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected a |
Immunogen | Immunogen: E Coli-derived human MR1 recombinant protein (Position: R23-D269). |
Other Names | [Major histocompatibility complex class I-related gene protein; MHC class I-related gene protein; Class I histocompatibility antigen-like protein; MR1] |
Gene, Accession # | [MR1], Gene ID: 3140, NCBI: NP_001181928.1, UniProt: Q95460 |
Catalog # | MBS1751261 |
Price | $315 |
Order / More Info | MR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: MR1 major histocompatibility complex, class I-related. 2. Hashimoto K, Hirai M, Kurosawa Y (Aug 1995). A gene outside the human MHC related to classical HLA class I genes. Science. 269 (5224): 693-5. 3. Yamaguchi H, Kurosawa Y, Hashimoto K (Nov 1998). Expanded genomic organization of conserved mammalian MHC class I-related genes, human MR1 and its murine ortholog. Biochem Biophys Res Commun. 250 (3): 558-64. |