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Antigenic Specificity | PAK3 (Serine/threonine-protein kinase PAK 3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The activated kinase, PAK3 (Serine/threonine-protein kinase PAK 3) acts on a variety of targets. PAK3 (Serine/threonine-protein kinase PAK 3) interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. PAK3 shows highly specific binding to the SH3 domains of phospholipase C-gamma and of adapter protein NCK. PAK3 is highly expressed in postmitotic neurons of the developing and postnatal cerebral cortex and hippocampus. Defects in PAK3 are the cause of non-specific X-linked nonsyndromic mental retardation type 30 (MRX30). |
Immunogen | Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human PAK3 (Serine/threonine-protein kinase PAK 3) |
Other Names | [Pak3, isoform D; CG14895 gene product from transcript CG14895-RD], [Pak3; anon-WO0118547.285; CG14895; D-Pak3; DmelCG14895; DmPAK3; dpak3; dPAK3; Dpak3; DPak3; DPAK3; PAK-3; pak3; PaK3; PAK3] |
Gene, Accession # | [PAK3], Gene ID: 41995, NCBI: NP_001262638.1 |
Catalog # | MBS418197 |
Price | $445 |
Order / More Info | PAK3 (Serine/threonine-protein kinase PAK 3) Antibody from MYBIOSOURCE INC. |
Product Specific References | Allen, K.M., et al, Nat. Genet. 20 (1), 25-30 (1998) Kitano, T., et al, Mol. Biol. Evol. 20 (8), 1281-1289 (2003) |