Edit |   |
---|---|
Antigenic Specificity | Human MYOC / Myocilin |
Clone | [4F8] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,k |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | 0.31 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA), RNA interference |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. |
Immunogen | Immunogen Description: MYOC (AAH29261, 36 a.a. ~ 135 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Other Names | [MYOC / Myocilin (clone 4F8) IHC-plus; MYOC; GLC1A; JOAG; JOAG1; Myocilin; TIGR; GPOA; Human MYOC; Myocilin], [MYOC; MYOC; GPOA; JOAG; TIGR; GLC1A; JOAG1; myocilin; GLC1A; TIGR] |
Gene, Accession # | [MYOC], Gene ID: 4653, NCBI: NP_000252.1, UniProt: Q99972 |
Catalog # | MBS245617 |
Price | $660 |
Order / More Info | Human MYOC / Myocilin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |