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Antigenic Specificity | C-JUN (pSer73) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | IgG concentration 0.5 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: C-JUN (pSer73). Rabbit anti Human c-Jun (pSer 73) recognizes c-Jun also known as p39 phosphorylated on Serine residue 73. The c-Jun transcription factor is encoded by the c-jun oncogene and dimerizes with c-Fos, JDP and ATF family members to form the AP-1 transcription factor. AP-1 is activated by a variety of stimuli including cytokines, stress and growth factors and plays a critical role in cellular processes ranging from proliferation to apoptosis.c-Jun becomes phosphorylated on Serine 63 and Serine 73 by MAPK8 (SAPK/JNK) and PLK3, which regulate c-Jun transcription. c-Jun has been implicated in early tumor development, invasion and metastasis and due to these findings has been identified as a target for cancer therapies. |
Immunogen | n/a |
Other Names | [Transcription factor AP-1; Transcription factor AP-1; transcription factor AP-1; jun proto-oncogene; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39], [JUN; JUN; AP1; AP-1; c-Jun; AP1] |
Gene, Accession # | [C-JUN], Gene ID: 3725, NCBI: P05412.2, UniProt: P05412 |
Catalog # | MBS224952 |
Price | $470 |
Order / More Info | C-JUN (pSer73) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |