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Antigenic Specificity | CBX2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CBX2 antibody detects endogenous levels of total CBX2. Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:21282530). Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) (By similarity). Plays a role in the lineage differentiation of the germ layers in embryonic development (By similarity). Involved in sexual development, ac |
Immunogen | Immunogen: A synthesized peptide derived from human CBX2 Subcellular Location: Nucleus. Tissue Specificity: Expressed during interphase and metaphase. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit Similarity: Pig (86%), Bovine (80%), Sheep (80%), Rabbit (82%) |
Other Names | [Cbx 2; CBX2; CBX2_HUMAN; CDC A6; CDCA6; Cell division cycle associated 6; Cell division cycle associated6; chromobox homolog 2 (Pc class homolog, Drosophila); Chromobox homolog 2; Chromobox homolog2; Chromobox protein homolog 2; hromobox homolog 2; M33; M33 polycomb like; MOD 2; MOD2; Modifier 3; Modifier3; Pc class homolog; Polycomb; SRXY5] |
Gene, Accession # | [CBX2], Gene ID: 84733, NCBI: NP_005180.1, UniProt: Q14781 |
Catalog # | MBS9609697 |
Price | $240, $280 |
Order / More Info | CBX2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |