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Antigenic Specificity | NGAL (Capture Ab) |
Clone | [H11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | 1 mg |
Concentration | 5 mg/ml |
Applications | Western Blot (WB), Lateral Flow (LF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: It specifically recognize the human NGAL. Lipocalin-2 (LCN2), also known as oncogene 24p3 or neutrophil gelatinase-associated lipocalin (NGAL), is a protein associated with neutrophil gelatinase. The 25-kD LCN2 protein is believed to bind small lipophilic substances such as bacteria-derived lipopolysaccharide (LPS) and formylpeptides and may function as a modulator of inflammation. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor. |
Immunogen | Immunogen: Recombinant human NGAL. |
Other Names | [NGAL (Capture Ab)], [LCN2; LCN2; 24p3; MSFI; NGAL; HNL; NGAL; NGAL] |
Gene, Accession # | [NGAL], Gene ID: 3934, NCBI: NP_005555.2, UniProt: P80188 |
Catalog # | MBS355004 |
Price | $520 |
Order / More Info | NGAL (Capture Ab) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Kjeldsen, L., Johnsen, A. H., Sengelov, H., Borregaard, N. Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase. J. Biol. Chem. 268: 10425-10432, 1993. 2. Flo TH, Smith KD, Sato S, Rodriguez DJ, Holmes MA, Strong RK, Akira S, Aderem A (December 2004). Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature 432 (7019): 917-21. 3. Schmidt-Ott KM, Mori K, Li JY, Kalandadze A, Cohen DJ, Devarajan P, Barasch J (February 2007). Dual action of neutrophil gelatinase-associated lipocalin. J. Am. Soc. Nephrol. 18 (2): 407-13. |