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Antigenic Specificity | MMP-7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | Size: 100 ug/200 ul |
Applications | ELISA, Western Blot, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes ~30 kDa of human MMP-7 protein. The other species are not tested. Matrix metalloproteinases (MMPs) belong to a family of proteinases that target many extracellular matrix proteins including additional proteinases, growth factors, cell surface receptors and adhesion molecules. MMPs contain common domain structures that include a signal sequence, a propeptide, a catalytic domain, and a hemopexin-like (Hpx) domain. The MMP activity requires proteolytic cleavage of MMPs in order to generate activie MMPs by release of the inhibitory propeptide domain from the whole molecules. MMP-2, MMP-3, MMP-7, MMP-9 and MMP-13 have been characterized as important factors for normal tissue remodeling during embryo development and wound |
Immunogen | Antigen Preparation: A synthetic peptide corresponding to the C-terminus of human MMP-7. This sequence is identical among bovine and monkey. |
Other Names | [Rabbit MMP-7; Matrix Metalloproteinase 7 (MMP-7); Matrilysin; PUMP-1], [MMP7; MMP7; MMP-7; MPSL1; PUMP-1; MPSL1; PUMP1] |
Gene, Accession # | [MMP-7 (Matrilysin)], Gene ID: 4316, NCBI: NP_002414.1, UniProt: P09237 |
Catalog # | MBS462082 |
Price | $285 |
Order / More Info | MMP-7 Antibody from MYBIOSOURCE INC. |
Product Specific References | Nick Di Girolamo, et al. Active Matrilysin (MMP-7) in Human Pterygia: Potential Role in Angiogenesis. Investigative Ophthalmology and Visual Science. 2001;42:1963-1968. |