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Antigenic Specificity | MARCH2 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | dog, guinea pig, human, mouse, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against MARCH2. It was validated on Western Blot using a cell lysate as a positive control.Target Description: MARCH2 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. MARCH2 may be involved in endosomal trafficking through interaction with STX6. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MARCH2 |
Other Names | [E3 ubiquitin-protein ligase MARCH2 isoform 1; E3 ubiquitin-protein ligase MARCH2; E3 ubiquitin-protein ligase MARCH2; membrane associated ring-CH-type finger 2; Membrane-associated RING finger protein 2; Membrane-associated RING-CH protein II; MARCH-II; RING finger protein 172] |
Gene, Accession # | [MARCH2], Gene ID: 51257, NCBI: NP_057580, UniProt: Q9P0N8 |
Catalog # | MBS3206768 |
Price | $335 |
Order / More Info | MARCH2 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |