SOD (Cu/Zn) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySOD (Cu/Zn)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse, bovine
Isotypen/a
Formatfluorescein (FITC) conjugate
Size0.1 mg
Concentration1mg/mL
ApplicationsWestern Blot (WB), Immunoprecipitation (IP), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionBackground Info: Detects a ~23kDa (human) and 19kDa (other species) proteins corresponding to the molecular mass of Cu/Zn superoxide dismutase (SOD) on SDS PAGE immunoblots. Scientific Background: Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2 to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2,5). In general, SODs play a major role in antioxidant defense mechanisms (4). There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two
Immunogenn/a
Other Names[Superoxide dismutase1; ALS1; IPOA; SOD1; SOD2; SODC; SOD; Cu Zn SOD], [Sod1; Sod1; CuZnSOD]
Gene, Accession #Gene ID: 24786, NCBI: NP_058746.1, UniProt: P07632
Catalog #MBS804950
Price$445
Order / More InfoSOD (Cu/Zn) Antibody from MYBIOSOURCE INC.
Product Specific References1.Adachi T., et al. (1992). Clin. Chim. Acta. 212: 89-102. 2.Barrister J.V., et al. (1987). Crit. Rev. Biochem. 22:111- 180. 3.Furukawa Y., O'Halloran T. (2006). Antioxidants & Redo Signaling. Vol 8, No 5,6. 4.Gao B., et al. (2003). Am J Physiol Lung Cell Mol Physiol 284: L917-L925. 5.Hassan H.M. (1988). Free Radical Biol. Med. 5: 377-385. 6.Kurobe N., et al. (1990) Biomedical Research. 11: 187- 194 7.Wispe J.R., et al. (1989) BBA. 994: 30-36. 8.Xiao-Hong Liu., et al. (1993) Brain Research. 625: 29-37.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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