Edit |   |
Antigenic Specificity | SOD (Cu/Zn) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse, bovine |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects a ~23kDa (human) and 19kDa (other species) proteins corresponding to the molecular mass of Cu/Zn superoxide dismutase (SOD) on SDS PAGE immunoblots. Scientific Background: Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2 to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2,5). In general, SODs play a major role in antioxidant defense mechanisms (4). There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two |
Immunogen | n/a |
Other Names | [Superoxide dismutase1; ALS1; IPOA; SOD1; SOD2; SODC; SOD; Cu Zn SOD], [Sod1; Sod1; CuZnSOD] |
Gene, Accession # | Gene ID: 24786, NCBI: NP_058746.1, UniProt: P07632 |
Catalog # | MBS804950 |
Price | $445 |
Order / More Info | SOD (Cu/Zn) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1.Adachi T., et al. (1992). Clin. Chim. Acta. 212: 89-102. 2.Barrister J.V., et al. (1987). Crit. Rev. Biochem. 22:111- 180. 3.Furukawa Y., O'Halloran T. (2006). Antioxidants & Redo Signaling. Vol 8, No 5,6. 4.Gao B., et al. (2003). Am J Physiol Lung Cell Mol Physiol 284: L917-L925. 5.Hassan H.M. (1988). Free Radical Biol. Med. 5: 377-385. 6.Kurobe N., et al. (1990) Biomedical Research. 11: 187- 194 7.Wispe J.R., et al. (1989) BBA. 994: 30-36. 8.Xiao-Hong Liu., et al. (1993) Brain Research. 625: 29-37. |