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Antigenic Specificity | TBK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TBK1 Polyclonal Antibody detects endogenous levels of TBK1 protein. The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The TANK binding kinase 1 encoded by TBK1 is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. |
Immunogen | Immunogen: Synthesized peptide derived from human TBK1 around the non-phosphorylation site of S172 |
Other Names | [Rabbit TBK1; TBK1; NAK; Serine/threonine-protein kinase TBK1; NF-kappa-B-activating kinase; T2K; TANK-binding kinase 1] |
Gene, Accession # | [TBK1], Gene ID: 29110, NCBI: NP_037386.1, UniProt: Q9UHD2 |
Catalog # | MBS9705313 |
Price | $130, $220, $325 |
Order / More Info | TBK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |