Ki67 (C-epitope) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKi67 (C-epitope)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentration0.68mg/ml IgG in antibody stabilization buffer
ApplicationsELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionThis antibody will detect both isoform 1 and isoform 2 in human. Ki-67 is a marker of cell proliferation and is detected in cells that are in G1-, S-, G2-, and M-phase of thecell cycle and absent in cells in GO phase (1). Ki-67 is used as a marker for cell proliferation of solidtumors and some hematological malignancies. It is associated with ribosomal RNA transcription, andinactivation of antigen Ki-67 leads to inhibition of ribosomal RNA synthesis. Ki-67 expression is used as amarker for determining the fraction of proliferating cells within a given population of tumor cells. It is alsoimportant for distinguishing between malignant and benign peripheral nerve sheath tumors. MBS541939 is usedas prognostic/predictive markers in breast
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 2950-3000 on human antigen MBS541939 isoform 1. Expression: Expression of this antigen occurs preferentially during late G1, S, G2 and M phases of the cell cycle, while in cells in G0 phase the antigen cannot be detected. Determinant: Mid-region
Other Names[Antigen identified by Ki 67; KIA; MKI67; Proliferation related Ki 67 antigen; RP11-380J17.2], [MKI67; MKI67; KIA; MIB-; MIB-1; PPP1R105]
Gene, Accession #[Ki67], Gene ID: 4288, NCBI: NP_002408.3, UniProt: P46013
Catalog #MBS541939
Price$390
Order / More InfoKi67 (C-epitope) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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