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Antigenic Specificity | Ki67 (C-epitope) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 0.68mg/ml IgG in antibody stabilization buffer |
Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody will detect both isoform 1 and isoform 2 in human. Ki-67 is a marker of cell proliferation and is detected in cells that are in G1-, S-, G2-, and M-phase of thecell cycle and absent in cells in GO phase (1). Ki-67 is used as a marker for cell proliferation of solidtumors and some hematological malignancies. It is associated with ribosomal RNA transcription, andinactivation of antigen Ki-67 leads to inhibition of ribosomal RNA synthesis. Ki-67 expression is used as amarker for determining the fraction of proliferating cells within a given population of tumor cells. It is alsoimportant for distinguishing between malignant and benign peripheral nerve sheath tumors. MBS541939 is usedas prognostic/predictive markers in breast |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 2950-3000 on human antigen MBS541939 isoform 1. Expression: Expression of this antigen occurs preferentially during late G1, S, G2 and M phases of the cell cycle, while in cells in G0 phase the antigen cannot be detected. Determinant: Mid-region |
Other Names | [Antigen identified by Ki 67; KIA; MKI67; Proliferation related Ki 67 antigen; RP11-380J17.2], [MKI67; MKI67; KIA; MIB-; MIB-1; PPP1R105] |
Gene, Accession # | [Ki67], Gene ID: 4288, NCBI: NP_002408.3, UniProt: P46013 |
Catalog # | MBS541939 |
Price | $390 |
Order / More Info | Ki67 (C-epitope) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |