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Antigenic Specificity | Wilms Tumor Protein |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. |
Immunogen | Immunogen: A synthesized peptide derived from human Wilms Tumor Protein. Subcellular Localization: Nucleus. Nucleus, nucleolus. Cytoplasm. Shuttles between nucleus and cytoplasm. Tissue Specificity: Expressed in the kidney and a subset of hematopoietic cells. |
Other Names | [Wilms tumor protein; WT33; WT1], [WT1; WT1; GUD; AWT1; WAGR; WT33; NPHS4; WIT-2] |
Gene, Accession # | [WT1], Gene ID: 7490, NCBI: NP_000369.3, UniProt: P19544 |
Catalog # | MBS179182 |
Price | $160, $340, $340 |
Order / More Info | Wilms Tumor Protein Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |