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Antigenic Specificity | ITGA8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ITGA8 antibody detects endogenous levels of total ITGA8. Function: Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.Subunit Structure: Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of a heavy and a light chain linked by a disulfide bond. Alpha-8 associates with beta-1.Similarity: Belongs to the |
Immunogen | Immunogen: A synthesized peptide derived from human ITGA8 Subcellular Location: Membrane. Tissue Specificity: Expressed in mesenchymal cells, including alveolar myofibroblasts, kidney mesangial cells and hepatic stellar cells and vascular and visceral smooth muscle (at protein level). |
Other Names | [Integrin alpha 8; Integrin alpha-8 heavy chain; Integrin alpha-8 light chain; ITA8_HUMAN; ITGA 8; ITGA8] |
Gene, Accession # | [ITGA8], Gene ID: 8516, NCBI: NP_003629.2, UniProt: P53708 |
Catalog # | MBS9609310 |
Price | $240, $280 |
Order / More Info | ITGA8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |