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Antigenic Specificity | LAG3 (Lymphocyte Activation Gene 3 Protein, LAG-3, Protein FDC, CD223, FDC) |
Clone | [12K124] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2B |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | ~0.5mg/ml after reconstitution |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes mouse LAG-3. Does not react with recombinant human LAG-3. LAG-3 is a member of the immunoglobulin superfamily (IgSF). The mature LAG-3 protein is a 496aa membrane protein with a 421aa extracellular region which contains four IgSF domains, a 21aa transmembrane region and a 54aa cytoplasmic region. LAG-3 shares <20% aa sequence homology with CD4, but has similar structure and binds to MHC class II with higher affinity. The mouse LAG-3 extracellular region shares 69% aa sequence identity with human LAG-3. |
Immunogen | Immunogen: Recombinant preotein corresponding to Ser23-Leu442 from mouse LAG-3 expressed in NS0 cell line. |
Other Names | [-LAG3 (Lymphocyte Activation Gene 3 Protein, LAG-3, Protein FDC, CD223, FDC)], [LAG3; LAG3; CD223; FDC; LAG-3] |
Gene, Accession # | Gene ID: 3902, NCBI: NP_002277.4, UniProt: P18627 |
Catalog # | MBS642763 |
Price | $680 |
Order / More Info | LAG3 (Lymphocyte Activation Gene 3 Protein, LAG-3, Protein FDC, CD223, FDC) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |