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Antigenic Specificity | TNIP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TNIP1 Antibody detects endogenous levels of TNIP1. Description: Inhibits NF-kappa-B activation and TNF-induced NF-kappa-B-dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG; proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway; blocks MAPK3/MAPK1 nuclear translocation and MAPK1-dependent transcription. Increases cell surface CD4(T4) antigen expression. Involved in the anti-inflammatory response of macrophages and positively regulates TLR-induced activation of CEBPB. Involved in the prevention of autoimmunity; this function implicates binding to polyubiquitin. Involved in leukocyte integrin activation during inflammation; this f |
Immunogen | Immunogen: A synthesized peptide derived from human TNIP1. Tissue Specificity: Ubiquitous. Strongly expressed in peripheral blood lymphocytes, spleen and skeletal muscle, and is weakly expressed in the brain. In peripheral blood mononucleocytes, isoform 4 is mainly expressed and isoform 1 and isoform 7 are almost not expressed. Expression of isoform 1 and isoform 7 increases in leukemic cells. |
Other Names | [ABIN 1; HIV-1 Nef-interacting protein; hVAN; KIAA0113; Naf1; Nef-associated factor 1; Nip40-1; TNFAIP3 interacting protein 1; TNFAIP3-interacting protein 1; TNIP-1; Tnip1; TNIP1_HUMAN; VAN; Virion-associated nuclear shuttling protein] |
Gene, Accession # | [TNIP1], Gene ID: 10318, NCBI: Q15025.2, UniProt: Q15025 |
Catalog # | MBS9611529 |
Price | $240, $280 |
Order / More Info | TNIP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |