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Antigenic Specificity | MAP1LC3A |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MAP1LC3A Antibody detects endogenous levels of total MAP1LC3A. Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents (1, 2). Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegenerative diseases, infection and cancer (3). Autophagy marker Light Chain 3 (LC3) was originally identified as a subunit of microtubule-associated proteins 1A and 1B (termed MAP1LC3) (4), and subsequently found to contain similarity to the yeast protein Apg8/Aut7/Cvt5 critical for autophagy (5). Three human LC3 isoforms (LC3A, LC3B, and LC3C) undergo post-translation |
Immunogen | Immunogen: Recombinant protein of human MAP1LC3A |
Other Names | [MAP1LC3; LC3; LC3A; MAP1ALC3; MAP1BLC3; MAP1LC3A] |
Gene, Accession # | [MAP1LC3A], Gene ID: 84557, NCBI: NP_115903.1, UniProt: Q9H492 |
Catalog # | MBS8516854 |
Price | $290 |
Order / More Info | MAP1LC3A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |