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Antigenic Specificity | GFR alpha 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | DEAE purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GFR alpha 3 Antibody: Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin. Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFRα and Ret receptor tyrosine kinase GFRbeta. Following the findings of GFRα-1 and -2, a novel receptor in GFRα family was identified very recently from human and mouse and designated GFRα-3. GFRα-3 binds persephin, thus, persephin, GFRα-3, and Ret PTK form a complex to transduce |
Immunogen | Immunogen: GFR alpha 3 antibody was raised against a 14 amino acid peptide near the center of murine GFR alpha 3. Buffer: GFR alpha 3 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [GFR alpha 3; Y15110; GFRalpha3; GDNF family receptor alpha-3; GDNF receptor alpha-3; glial cell line derived neurotrophic factor family receptor alpha 3], [Gfra3; Gfra3; Y15110; GFRalpha3; GDNF receptor alpha-3; GDNFR-alpha-3; GFR-alpha-3] |
Gene, Accession # | [Gfra3], Gene ID: 14587, NCBI: AB008833, UniProt: O35118 |
Catalog # | MBS151276 |
Price | $375 |
Order / More Info | GFR alpha 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |