Edit |   |
---|---|
Antigenic Specificity | Caspase 12 (IN) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-Caspase-12 (IN) [Rabbit antibody to peptide corresponding to aa 100-116 of mouse caspase-12. Recognizes human, mouse and rat caspase-12.]. This antibody recognizes human, mouse, and rat caspase-12 (approx. 53 kD). Three distinct signaling pathways lead to programmed cell death. The death receptor and mitochondrial pathways are the main pathways in which the proteases caspase-8 and caspase-9, respectively, are involved. Endoplasmic reticulum (ER) stress is the third pathway, and caspase-12 is involved. Caspase-12, localized in the ER, is activated by ER stress and mediates ER stress-induced apoptosis. Several proteins that are associated with Alzheimer's disease, including gamma -secretase, presenilin, and beta -amyloid pre |
Immunogen | Antigen: Peptide corresponding to aa 100- 116 of mouse caspase-12 |
Other Names | [Caspase-12 (IN); Caspase-12 (IN)], [CASP12; Caspase-12] |
Gene, Accession # | Gene ID: 479458, NCBI: NP_001070704.1, UniProt: Q075B4 |
Catalog # | MBS194391 |
Price | $415 |
Order / More Info | Caspase 12 (IN) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |