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Antigenic Specificity | Replication Protein A2 (RPA2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of 34kDa, identified as a subunit of Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB). RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). It is involved in DNA replication, repair, and recombination. RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase (pol) alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation. |
Immunogen | Immunogen: Recombinant human full-length Replication protein A2 (RPA2) protein |
Other Names | [p32; p34; REPA2; Replication protein A 32kDa subunit; Replication protein A 34kDa subunit; Replication protein A2; RF-A protein 2; Rf-A2; RFA; RP-A p32; RP-A p34; RP21C; RPA32; RPA34; RpLP1; RpP2] |
Gene, Accession # | [RPA2], Gene ID: 6118, NCBI: NP_002937.1, UniProt: P15927 |
Catalog # | MBS4381234 |
Price | $190, $340, $340 |
Order / More Info | Replication Protein A2 (RPA2) Antibody from MYBIOSOURCE INC. |
Product Specific References | Kenny MK, et. al. Journal of Biological Chemistry, 1990, 265(13):7693-7700. |