Edit |   |
---|---|
Antigenic Specificity | UNG/Udg Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Uracil-DNA glycosylase, also known as UNG or UDG, is a human gene though orthologs exist ubiquitously among prokaryotes and eukaryotes and even in some DNA viruses. The first uracil DNA-glycosylase was isolated from Escherichia coli. This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as |
Immunogen | Immunogen: E Coli-derived human UNG recombinant protein (Position: R219-L313). Human UNG shares 92.6% amino acid (aa) sequence identity with mouse UNG. Subcellular Localization: Isoform 1: Mitochondrion. Tissue Specificity: Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells. |
Other Names | [Uracil-DNA glycosylase; UDG; 3.2.2.27; UNG; DGU; UNG1; UNG15] |
Gene, Accession # | [UNG], Gene ID: 7374, NCBI: NP_003353.1, UniProt: P13051 |
Catalog # | MBS1750690 |
Price | $315 |
Order / More Info | UNG/Udg Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |